bloodbrainbarrier相关论文
Salvianolic acid A (SAA) is a water-soluble component from the root of Salvia Miltiorrhiza Bge,a traditional Chinese med......
Cerebral ischemia-induced occludin degradation promotes blood brain barrier endothelial cell apoptos
Intracerebral hemorrhage is the most dangerous complication in tPA thrombolytic therapy for ischemic stroke,which occurs......
Study on the cell penetrating peptide targeting to brain(PTB)based on RVG29R9 and PTB modified lipos
It was reported that the conjugate compound of nona-arginine(R9)and 29 peptides from rabies virus glycoprotein(RVG),a su......
Penetration of verapamil across blood brain barrier following cerebral ischemia depending on both pa
Aim: Blood brain barrier (BBB) dysfunction is a common facet of cerebral ischemia, and the alteration of drug transporte......
Progesterone has been shown to be a neuroprotective agent for ischemic damage.Progesterone reduces infarct volume and pr......
Clematichinenoside protects blood brain barrier against ischemic stroke superimposed on systemic inf
Suppression of excessive inflammation can ameliorate blood brain barrier (BBB) injury, which shows therapeutic potential......
Exposure to acute hypobaric hypoxia(AHH)during ascent to high altitudes(>3,500 m)pose a big challenge for those without ......
The role of cerebral endothelium in the pathogenesis of vascular dementia and the related Chinese he
Vascular dementia (VaD),the second most common type of dementia after Alzheimers disease (AD),is characterized by the pr......
Cerebral amyloid angiopathy(CAA)refers to the deposition of β-amyloid(Aβ)peptides in the wall of brain vasculature,com......
Objective: This study is to evaluate the effectiveness of treating glioma in combination with drugs multiply by comparin......
Progress in Research of Penetrating the Blood Brain Barrier and its Neurotoxicity by means of Nano-p
OBJECTIVES: This review mainly summarized the progress in research of crossing blood brain barrier by nano-pharmaceutics......
Activation of AMP-activated protein kinase alleviates high glucose-induced dysfunction of brain endo
AIM The aim of this study was to elucidate the molecular mechanisms underlying disruption of the blood-brain-barrier in ......
Preliminary Study of Dynamic CT Perfusion Imaging in Rats Traumatic Brain Injury and Its Related Pat
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Platelet activating factor mediates blood brain barrier dysfunction through up-regulation of MMP-9 i
Platelet-activating factor (PAF) was a lipid mediator that aggravated brain injury after cerebral ischemia and reperfusi......
Therapeutic neuroprotective effects of Ginkgolide B on cortex and basal ganglia in a rat model of tr
Cerebral ischemia and reperfusion is one of the leading causes for death and severe disabilities in the world and often ......
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Objective: The present study examined effects of alpha-mangostin(α-MG)supplementation on cerebral blood flow(CBF),and b......
Melatonin alleviates lipopolysaccharide-compromised integrity of blood brain barrier by activation o
The integrity and function dysfunction of the blood brain barrier (BBB) is considered to be an early event in the pathog......
Clematichinenoside protects blood brain barrier against ischemic stroke superimposed on systemic inf
Suppression of excessive inflammation can ameliorate blood brain barrier (BBB) injury, which shows therapeutic potential......
IMM-H004 prevents toxicity induced by delayed treatment of tPA in a rat model of focal cerebral isch
OBJECTIVE Ischemic stroke is currently treated with thrombolytic therapy with a drawback to induce hemorrhagic transform......
Aim To investigate the therapic effects of Pae on brain ischemia-reperfusion injury in rat.To observe neurological score......
Activatable Small-Molecule Photoacoustic Probes that Cross the Blood-Brain Barrier for Visualization
Copper enrichment in the brain is highly related to Alzheimers disease(AD)pathogenesis,but in vivo tracing of Cu2+in the......
The effects of tea polyphenols (TP) on mitochondrial lipid peroxidation, blood brain barrier (BBB) permeability, mitocho......
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Effects of matrix metalloproteinase 9 inhibition on the blood brain barrier and inflammation in rats
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Diffusion Efficiency and Bioavailability of Resveratrol Administered to Rat Brain by Different Route
Resveratrol possesses anti-tumor activities against central nervous system (CNS) tumors in vitro but has not yet bee......
The Property Based Design of Inhibitors of Glycosphingolipid Synthesis that Act Within the Central N
Synthesis inhibition is the basis for the treatment of type 1 Gaucher disease by the glucosylceramide synthase (GCS)......
血脑屏障是隔离外周体循环和中枢神经系统的屏障结构。它可以选择性允许血液中的一些物质通过脑微血管内皮细胞进入大脑中。除了脑......
Matrix metalloproteinase-9 expression and blood brain barrier permeability in the rat brain after ce
BACKGROUND: The integrity of the blood brain barrier (BBB) plays an important role in the patho-physiological process of......
Effects of the mitochondrial calcium uniporter on cerebral edema in a rat model of cerebral ischemia
The present study investigated the effects of the mitochondrial calcium uniporter inhibitor ruthenium red and the agonis......
The blood brain barrier represents a formidable obstacle for the transport of most systemati-cally administered neurodia......
目的 观察心肺复苏(CPR)早期大鼠脑组织基质金属蛋白酶-9(MMP-9)和血脑屏障的变化及MMP-9抑制剂SB-3CT对其的作用.方法 将动物随机......
Hyperammonemia,brain edema and blood-brain barrier alterations in prehepatic portal hypertensive rat
AIM: To study the blood-brain barrier integrity, brain edema,animal behavior and ammonia plasma levels in prehepatic por......
Effects of salidroside pretreatment on expression of tumor necrosis factor-alpha and permeability of
Objective:To observe changes in expression of tumor necrosis factor(TNF)-alpha and permeability of blood brain barrier a......
脑出血是脑卒中的第二大类型,而且发病急,进展快,止血药物的作用不大,其较高的病死率及致残率给社会及家庭带来沉重负担.高压氧的......
血脑屏障（ BBB）是维持中枢神经系统（ CNS）内环境稳定的结构基础，当血脑屏障受到破坏后，会导致一系列CNS相关性疾病的发生。近几年的研究......
Current treatments for cancer and the central nervous system diseases are limited,partly due to the difficulties posed b......
Background: Cytridini triphophatis(CTP) takes part in the synthesis of phospholipid and nucleic acid directly, and makes......
Background:After intracerebral hemorrhage,besides take part in blood coagulation,plasma thrombin also is an important ne......
Bloodletting Puncture at Hand Twelve Jing-Well Points Relieves Brain Edema after Severe Traumatic Br
Objective: To investigate whether blood-brain barrier (BBB) served a key role in the edema-relief effect of bloodletting......
目的 分析脑转移瘤全脑照射20 Gy后辅以化学治疗与单纯放射治疗脑转移瘤,评价两种治疗方法的疗效和预后因素.方法 回顾性分析经病......
血脑屏障(blood brain barrier,BBB)是存在于血液和脑组织之间的屏障系统,可保持中枢神经系统内环境的相对稳定.脑缺氧缺血可导致B......
目的：研究脑损伤后高血糖对大鼠血-脑屏障通透性的影响。方法：雄性Wistar大鼠40只，随机分为4组；正常对照组（Ⅰ组），高血糖组（Ⅱ组），脑损伤后正......
目的 观察静脉输注不同剂量异丙酚对大鼠血脑屏障（BBB）通透性的影响。方法 30只成年大鼠随机分为三组：对照组（C组，不用全麻药，n＝6），异丙酚70......
目的 探讨七氟醚对成年及老年大鼠血脑屏障通透性的影响。方法 用依文氏蓝（EB）染色及光镜、电镜观察成年及老年大鼠吸入1MAC或1.5MAC......
